Vol. 33 | Vol. 33 (2) - 2022 | Column: CONSUMER PERSPECTIVE

Antioxidants, prooxidants & metabolism: Is everything that is sold safe? if our cells could talk!

by

ANTONIO J. RODRÍGUEZ DÍAZ
RM FARMAMÉDICAL Granada, Spain

ABSTRACT

If an unbalanced oxidative stress is detrimental to health, using an antioxidant that has not demonstrated its pro-oxidant capacity can be even worse for health.
How many antioxidants exist? How many have shown that they are in fact not pro-oxidants at the usual dose? And how do these antioxidants influence the metabolism of an individual? In the Stance4Health project, funded by the European Union’s Horizon 2020 research and innovation program, these situations have been evaluated in vitro and by applying an innovative metabolomics test to urine samples collected on filter paper in humans. Stance4Health, is innovatively applying these research findings to achieve an intelligent personalized nutrition service.

INTRODUCTION
During aerobic cell metabolism, the generation of reactive oxygen species and other free radicals is a normal and necessary process that is generally compensated by endogenous antioxidant defence systems, which help maintain redox balance. When there is an overproduction of reactive oxygen species together with a deficit of enzymatic and non-enzymatic antioxidants, a redox imbalance is produced, which is especially relevant for health.

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